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Table 4 Macrophage count per cm2 at weeks 52 and 104. The lungs of 5 animals were examined for each data point

From: Comparative carcinogenicity study of a thick, straight-type and a thin, tangled-type multi-walled carbon nanotube administered by intra-tracheal instillation in the rat

 

Vehicle

MWCNT-A

MWCNT-B

Crocidolite

 

0.5 mg

1.0 mg

0.5 mg

1.0 mg

1.0 mg

52 wks

69 ± 26

258 ± 22***

268 ± 35***

412 ± 46***

499 ± 49***

130 ± 50*

104 wks

72 ± 9

235 ± 104**

367 ± 113***

393 ± 31***

426 ± 46***,#

109 ± 67

  1. *,**,*** Different from the vehicle control at p < 0.05, p < 0.01, p<0.001
  2. # Different from 52 weeks at p < 0.05
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Particle and Fibre Toxicology

ISSN: 1743-8977

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