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Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Diesel exhaust particle exposure reduces expression of the epithelial tight junction protein Tricellulin

Fig. 5

Early life exposure to DEP causes a reduction in Tricellulin expression in the lung. a Neonatal mice exposed to aerosolized DEP exhibit a reduction in Tricellulin mRNA in the lung 2 weeks post final exposure as measured by RT-qPCR. Unequal variances t-test, *P < 0.05, N = 11 (FA) or N = 12 (DEP). b Neonatal mice exposed to aerosolized DEP exhibit a reduction in Tricellulin protein in the lung 2 weeks post final exposure as measured by Western blot. Student’s t-test, *P < 0.05, N = 7 per treatment

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