Even lobar deposition of poorly soluble gold nanoparticles (AuNPs) is similar to that of soluble silver nanoparticles (AgNPs)

Table 3 Gold concentration in each lung lobe after 5-day exposure

Lobes	Retention (μg/g)^a	Lung weight (g)^b	Retention (μg)/lobe^c
RCr	11.13 ± 2.44	0.11 ± 0.01	1.23 ± 0.21 (7.85%)
RM	15.64 ± 2.45	0.14 ± 0.01	2.17 ± 0.38 (13.86%)
RCa	14.85 ± 1.98	0.32 ± 0.02	4.70 ± 0.49 (30.06%)
RA	14.70 ± 3.93	0.13 ± 0.02	1.84 ± 0.46 (11.77%)
RL	14.39 ± 2.12	0.69 ± 0.04	9.93 ± 0.96 (63.54%)
LL	13.76 ± 2.63	0.42 ± 0.04	5.70 ± 0.55 (36.46%)
Total lung	14.12 ± 2.03	1.11 ± 0.08	15.63 ± 1.33

(mean ± S.D); 5 animals; * P < 0.05; comparing RCa, RL, LL, and total lung; RCr, right cranial; RM, right median; RCa, right caudal; RA, right accessory lobe; RL, whole right lung (RCr + RM + RCa + Ra); LL, left lung; Total lung, (RL + LL); a) μg/L (ICP-MS; ppb) × 0.005 L (end of volume) / lobe weight = gold concentration in 1 g; b) Each lobe weight; c) Retained mass concentration x lung lobe weight = gold concentration in lobe;

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