The pulmonary toxicity of carboxylated or aminated multi-walled carbon nanotubes in mice is determined by the prior purification method

Table 2 Suspension characteristics of MWCNTs in dispersion medium^aused for oropharyngeal aspiration in mice

MWCNT	Size distribution^b		pDi	Zeta potential (mV)
MWCNT	Z-Avg Diameter nm	Multi-mode distribution peaks Diameter nm (% peak area)	pDi	Zeta potential (mV)
NC7000	399 ± 6	259 ± 36 (55%) 1652 ± 1194 (45%)	0.57	−16.8 ± 1.4
TP7000	1626 ± 265	683 ± 205 (82%) 193 ± 91 (19%)	1	− 14.6 ± 1.1
TP-COOH	932 ± 49	716 ± 337 (83%) 174 ± 39 (17%)	0.83	−15.7 ± 1.4
TP-NH2	1590 ± 114	992 ± 214 (75%) 267 ± 39 (25%)	0.97	− 18.0 ± 0.4
CP7000	1359 ± 169	719 ± 403 (60%) 200 ± 12 (40%)	1	−15.3 ± 1.4
CP-COOH	484 ± 48	637 ± 145 (57%) 153 ± 29 (43%)	0.72	− 24.0 ± 0.9
CP-NH2	1897 ± 216	918 ± 85 (100%)	0.80	−17.6 ± 1.2
Mitsui-7	985 ± 73	919 ± 227 (92%) 3292 ± 2685 (8%)	0.46	−14.8 ± 0.8

^aMWCNTs were diluted in dispersion medium (0.1% Pluronic solution in sterile DPBS + 3% BSA) to a concentration of 50 μg/ml prior to DLS analysis
^bValues are mean ± standard deviation of 4–5 independent measurements. Multimode distribution is presented as diameter of different peaks and % area occupied by that peak (relative contribution)

ISSN: 1743-8977