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Fig. 12 | Particle and Fibre Toxicology

Fig. 12

From: Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice on a high-fat diet

Fig. 12

Probiotic supplementation alters the microbial profile and decreases the expansion of Proteobacteria. a Quantification by qPCR of (a) Eubacteria (log scale), b 100% stacked columns representing the percentages of major phyla within the lungs of C57Bl/6 wildtype mice on high-fat (HF) diet exposed to either saline (control) or diesel exhaust particles (DEP – 35 μg PM) twice a week for a total of 30 days alongside a dose of 0.3 g/day (~ 7.5 × 107 cfu/day) of Ecologic® Barrier probiotics in the drinking water over the course of the exposures. Data are depicted as mean ± SEM with *p < 0.05 compared to HF Control, ‡p < 0.05 compared to HF DEP by two way ANOVA. The saline group included on the graph is a negative control reference and was not included in the two way ANOVA analysis

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Particle and Fibre Toxicology

ISSN: 1743-8977

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