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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Titanium dioxide nanoparticles impair the inner blood-retinal barrier and retinal electrophysiology through rapid ADAM17 activation and claudin-5 degradation

Fig. 4

TiO2-NP-mediated ADAM17 activation improved endothelial cell migration. Both the representative images and quantified data demonstrated TiO2-NP improved endothelial cell migration. This phenomenon could be prevented in the presence of GM6001 or TAPI-2. a Transwell assay. b Scratch assay. (*p < 0.05, **p < 0.01, ***p < 0.001, indicates statistically significant difference from the control treatment; ### p < 0.001 indicates statistically significant difference from the TiO2-NP-treated group)

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Particle and Fibre Toxicology

ISSN: 1743-8977

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