| Main group | |||||||
---|---|---|---|---|---|---|---|---|
Sex | Male | Female | ||||||
Concentration (mg/m3) | 0 | 0.8 | 4 | 20 | 0 | 0.8 | 4 | 20 |
Absolute organ weight (g) | ||||||||
 Brain | 1.767 ± 0.017 | 1.758 ± 0.041 | 1.706 ± 0.039a | 1.683 ± 0.030b | 1.668 ± 0.020 | 1.659 ± 0.056 | 1.624 ± 0.097 | 1.630 ± 0.056 |
 Heart | 0.646 ± 0.026 | 0.603 ± 0.054 | 0.536 ± 0.022 | 0.467 ± 0.032## | 0.474 ± 0.034 | 0.445 ± 0.010 | 0.435 ± 0.036 | 0.422 ± 0.022a |
 Lung | 0.330 ± 0.031 | 0.350 ± 0.026 | 0.349 ± 0.016 | 0.309 ± 0.022 | 0.273 ± 0.050 | 0.286 ± 0.015 | 0.299 ± 0.016 | 0.329 ± 0.071 |
 Liver | 5.803 ± 0.257 | 5.282 ± 0.479 | 4.513 ± 0.476b | 3.369 ± 0.237b | 3.664 ± 0.300 | 3.493 ± 0.102 | 3.192 ± 0.274a | 3.082 ± 0.194b |
 Spleen | 0.457 ± 0.037 | 0.438 ± 0.034 | 0.330 ± 0.021b | 0.214 ± 0.026b | 0.329 ± 0.046 | 0.317 ± 0.023 | 0.274 ± 0.016a | 0.220 ± 0.010b |
 Kidney | 1.384 ± 0.074 | 1.319 ± 0.077 | 1.180 ± 0.082b | 1.031 ± 0.068b | 0.999 ± 0.068 | 0.978 ± 0.038 | 0.926 ± 0.051 | 0.895 ± 0.066a |
Relative organ weight (%) | ||||||||
 Brain | 0.934 ± 0.049 | 0.978 ± 0.078 | 1.083 ± 0.107 | 1.383 ± 0.119b | 1.274 ± 0.064 | 1.309 ± 0.073 | 1.359 ± 0.054 | 1.507 ± 0.073b |
 Heart | 0.342 ± 0.021 | 0.333 ± 0.009 | 0.340 ± 0.024 | 0.382 ± 0.015b | 0.362 ± 0.017 | 0.351 ± 0.011 | 0.364 ± 0.016 | 0.390 ± 0.020a |
 Lung | 0.175 ± 0.022 | 0.194 ± 0.010 | 0.221 ± 0.016b | 0.254 ± 0.020b | 0.208 ± 0.033 | 0.226 ± 0.009 | 0.251 ± 0.031 | 0.304 ± 0.066b |
 Liver | 3.064 ± 0.091 | 2.923 ± 0.110 | 2.841 ± 0.085b | 2.757 ± 0.112b | 2.791 ± 0.011 | 2.753 ± 0.077 | 2.667 ± 0.115 | 2.844 ± 0.084 |
 Spleen | 0.241 ± 0.023 | 0.242 ± 0.009 | 0.208 ± 0.009b | 0.175 ± 0.014b | 0.250 ± 0.025 | 0.250 ± 0.016 | 0.230 ± 0.021 | 0.204 ± 0.011b |
 Kidney | 0.732 ± 0.054 | 0.732 ± 0.049 | 0.745 ± 0.024 | 0.843 ± 0.023b | 0.761 ± 0.021 | 0.771 ± 0.042 | 0.775 ± 0.050 | 0.826 ± 0.048 |