Fig. 6

Characterization of CeO₂-induced macrophage recruitment and polarization in mice. Representative lung tissue sections of C57Bl/6 mice exposed to Saline or CeO₂ NP (5 or 50 μg, observation at 28 days), after immunostaining for CD107b, as a marker of total number of macrophages (Panel a). Original magnification × 200. Quantification of CD107b positive cells (Panel b). Representative lung tissue sections of mice exposed to Saline or CeO₂ NP (5 or 50 μg, observation at 28 days), after immunostaining for CD80 (Panel c and d for quantification), CD68 (Panel e and f for quantification), iNOS (Panel g and h for quantification), CD206 (Panel i and j for quantification), CD163 (Panel k and l for quantification) or Arginase 1 (Panel m and n for quantification). Original magnification × 200. Legends as in Fig. 4