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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: The combined effect of food additive titanium dioxide and lipopolysaccharide on mouse intestinal barrier function after chronic exposure of titanium dioxide-contained feedstuffs

Fig. 3

The translocation of TiO2 particles from the gastrointestinal tract. (a) Fecal images of mice fed with control feed, 1% (w/w) TiO2 NPs or TiO2 MPs mixed feed for 21 days of exposure. Similar feces were observed from day 21 onwards (from day 21 to the end of exposure). (b) TEM images of ileum mucosa in mice after fed with TiO2 NPs or TiO2 MPs-mixed feed for 6 months. Red arrows indicate TiO2 particles internalized into intracellular vesicles. Blue arrows indicate microvilli. (c) Ti content in mice blood cells (μg/g dry weight) after feeding with control, 1% (w/w) TiO2 NPs or 1% (w/w) TiO2 MPs-mixed feed (mean ± SD, n=5) for up to 1, 3, 6 months

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Particle and Fibre Toxicology

ISSN: 1743-8977

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