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Table 1 The dispersion state of TiO2 particles in ultrapure water, artificial gastric/intestinal juice (AGJ/AIJ)

From: The combined effect of food additive titanium dioxide and lipopolysaccharide on mouse intestinal barrier function after chronic exposure of titanium dioxide-contained feedstuffs

Material Ultrapure water AGJ AIJ
Hydrodynamic diameter(nm) PDI Zeta-potential(mV) Hydrodynamic diameter(nm) PDI Zeta-potential(mV) Hydrodynamic diameter(nm) PDI Zeta-potential(mV)
TiO2 NPs a 942.6±319.8 0.90±0.11 −18.37±1.04 1350±248.95 0.99±0.02 2.37±0.92 805.3±265.0 0.83±0.17 −23.67±1.68
TiO2 MPs a 1071.9±128.7 0.95±0.08 −15.37±0.35 1497±366.38 1.00±0.00 2.15±0.99 1194.3±183.6 0.99±0.02 −13.53±0.45
TiO2 NPs-mixed feed NT NT NT 1560.7±561.9b 0.97±0.05b −3.17±0.26b 348.2±54.8c 0.47±0.10c −6.48±1.34c
TiO2 MPs-mixed feed NT NT NT 1636.4±722.8b 0.97±0.09b −0.92±1.22b 670.3±286.0c 0.79±0.18c −13.03±2.03c
  1. Notes. a: Hydrodynamic diameters, PDI and zeta potential of TiO2 particles after being suspended in ultrapure water, AGJ or AIJ (the final test concentration is 0.5 mg/mL) respectively. b: Hydrodynamic diameters, PDI and zeta potential of particles was tested after TiO2 NPs or TiO2 MPs-mixed feed being digested in AGJ for 2 h (The final test dose is 0.25 mg/mL TiO2). c: Hydrodynamic diameters, PDI and zeta potential of particles was tested after TiO2 NPs or TiO2 MPs-mixed feed being digested in AGJ for 2 h followed by further digestion in AIJ for 2.5 h (The final test dose is 0.125 mg/mL TiO2). NT:no test; PDI: polydispersity index