Skip to main content

Table 4 Villi height/ crypt depth ratio in the small intestine after treatment with TiO2 and LPS

From: The combined effect of food additive titanium dioxide and lipopolysaccharide on mouse intestinal barrier function after chronic exposure of titanium dioxide-contained feedstuffs

 

Duodenum villi height/ crypt depth ratio

Jejunum villi height/ crypt depth ratio

Ileum villi height/ crypt depth ratio

Group

1 month (n=15)

3 months (n=5)

6 months (n=5)

1 month (n=15)

3 months (n=5)

6 months (n=5)

1 month (n=15)

3 months (n=5)

6 months (n=15)

C

3.21±0.56

3.74±0.79

4.32±0.45

3.55±0.46

3.4±0.31

4.08±0.65

1.96±0.29

1.58±0.13

1.93±0.28

L

4.45±0.84a

1.95±0.63a

3.51±0.49a

3.98±0.69

3.25±0.42

3.15±0.67

1.67±0.12a

1.62±0.07

1.89±0.38

NP

3.85±0.70a

3.99±0.65

3.89±1.08

4.10±0.80

3.61±0.71

4.01±0.50

1.65±0.12a

2.05±0.24a

1.78±0.14

NP+L

3.31±0.65b, c

2.86±0.46b, c

3.62±0.57

5.18±1.44a, b, c

4.74±0.96a, b

3.78±0.24

1.78±0.21c

1.77±0.15

2.03±0.28

MP

4.41±0.60a, c

4.27±0.31

4.79±1.04

4.62±0.7a

5.03±0.92a, c

4.86±0.43c

1.69±0.12

1.79±1.61a

2.02±0.34c

MP+L

3.74±0.85b, e

3.72±0.48b, d

4.28±1.11

3.69±0.66d, e

3.63±0.44d, e

3.93±0.54d

1.41±0.14a, b, d, e

1.68±0.07

1.92±0.29

  1. Note: a, b, c, d, e, f represent statistically significant differences when compared to C, L, NP, (NP + L) and MP group respectively, P< 0.05