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Table 4 Villi height/ crypt depth ratio in the small intestine after treatment with TiO2 and LPS

From: The combined effect of food additive titanium dioxide and lipopolysaccharide on mouse intestinal barrier function after chronic exposure of titanium dioxide-contained feedstuffs

  Duodenum villi height/ crypt depth ratio Jejunum villi height/ crypt depth ratio Ileum villi height/ crypt depth ratio
Group 1 month (n=15) 3 months (n=5) 6 months (n=5) 1 month (n=15) 3 months (n=5) 6 months (n=5) 1 month (n=15) 3 months (n=5) 6 months (n=15)
C 3.21±0.56 3.74±0.79 4.32±0.45 3.55±0.46 3.4±0.31 4.08±0.65 1.96±0.29 1.58±0.13 1.93±0.28
L 4.45±0.84a 1.95±0.63a 3.51±0.49a 3.98±0.69 3.25±0.42 3.15±0.67 1.67±0.12a 1.62±0.07 1.89±0.38
NP 3.85±0.70a 3.99±0.65 3.89±1.08 4.10±0.80 3.61±0.71 4.01±0.50 1.65±0.12a 2.05±0.24a 1.78±0.14
NP+L 3.31±0.65b, c 2.86±0.46b, c 3.62±0.57 5.18±1.44a, b, c 4.74±0.96a, b 3.78±0.24 1.78±0.21c 1.77±0.15 2.03±0.28
MP 4.41±0.60a, c 4.27±0.31 4.79±1.04 4.62±0.7a 5.03±0.92a, c 4.86±0.43c 1.69±0.12 1.79±1.61a 2.02±0.34c
MP+L 3.74±0.85b, e 3.72±0.48b, d 4.28±1.11 3.69±0.66d, e 3.63±0.44d, e 3.93±0.54d 1.41±0.14a, b, d, e 1.68±0.07 1.92±0.29
  1. Note: a, b, c, d, e, f represent statistically significant differences when compared to C, L, NP, (NP + L) and MP group respectively, P< 0.05