TY - JOUR AU - van den Brule, Sybille AU - Rappe, Margaux AU - Ambroise, Jérôme AU - Bouzin, Caroline AU - Dessy, Chantal AU - Paquot, Adrien AU - Muccioli, Giulio G. AU - Lison, Dominique PY - 2021 DA - 2021/02/09 TI - Diesel exhaust particles alter the profile and function of the gut microbiota upon subchronic oral administration in mice JO - Particle and Fibre Toxicology SP - 7 VL - 18 IS - 1 AB - Ambient air pollution by particulate matters, including diesel exhaust particles (DEP), is a major cause of cardiovascular and metabolic mortality worldwide. The mechanisms by which DEP cause these adverse outcomes are not completely understood. Because the gut microbiota controls cardiovascular and metabolic health, we hypothesized that the fraction of inhaled DEP which reach the gut after mucociliary clearance and swallowing might induce gut dysbiosis and, in turn, contribute to aggravate or induce cardiovascular and metabolic diseases. SN - 1743-8977 UR - https://doi.org/10.1186/s12989-021-00400-7 DO - 10.1186/s12989-021-00400-7 ID - van den Brule2021 ER -