From: Differential effects of intense exercise and pollution on the airways in a murine model
 | DEP effect | Exercise effect | Interaction effect |
---|---|---|---|
Early ventilatory response | – | Altered breathing pattern | – |
Airway hyperreactivity | – | ↓ | – |
Airway inflammation | |||
 BAL Neutrophils | ↑ | – | – |
DC recruitment | |||
 CD11b+CD103− DC | ↑ | – | – |
 moDC | ↑ | – | – |
Airway permeability | |||
 Serum SP-D | ↑ | ↑ | ↑↑ |
 Serum Uric Acid | – | ↑ | – |
 BAL protein levels | – | – | – |
Airway integrity | |||
 OCLN mRNA expression | ↓ | – | – |
 ZO-1 mRNA expression | ↓ | – | – |
 Cldn-1 mRNA expression | ↑ | – | – |
 Cldn-3 mRNA expression | – | ↑ | – |
 Cldn-4 mRNA expression | – | – | – |
 Cldn-18 mRNA expression | – | ↑ | – |