Skip to main content

Table 1 Main findings

From: Differential effects of intense exercise and pollution on the airways in a murine model

 

DEP effect

Exercise effect

Interaction effect

Early ventilatory response

–

Altered breathing pattern

–

Airway hyperreactivity

–

↓

–

Airway inflammation

 BAL Neutrophils

↑

–

–

DC recruitment

 CD11b+CD103− DC

↑

–

–

 moDC

↑

–

–

Airway permeability

 Serum SP-D

↑

↑

↑↑

 Serum Uric Acid

–

↑

–

 BAL protein levels

–

–

–

Airway integrity

 OCLN mRNA expression

↓

–

–

 ZO-1 mRNA expression

↓

–

–

 Cldn-1 mRNA expression

↑

–

–

 Cldn-3 mRNA expression

–

↑

–

 Cldn-4 mRNA expression

–

–

–

 Cldn-18 mRNA expression

–

↑

–

  1. Table 1 shows the major changes induced by DEP exposure (independently from exercise), by exercise (independently from DEP exposure) and by the interaction between DEP exposure and exercise. ↑ represents a significant increase in comparison to the non-exposed or non-exercised groups and ↓ represents a significant decrease in comparison to the non-exposed or non-exercised groups