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Fig. 1 | Particle and Fibre Toxicology

Fig. 1

From: Upregulation of ACE2 and TMPRSS2 by particulate matter and idiopathic pulmonary fibrosis: a potential role in severe COVID-19

Fig. 1

Expression of ACE2 and TMPRSS2 in pulmonary fibrosis tissue. Masson’s trichrome, Picro Sirius Red staining and immunohistochemistry for ACE2 and TMPRSS2 were performed in continuous lung tissue sections from four IPF patients on behalf of one patient. The fibrotic areas, stained as blue in Masson’s trichrome or red in Picro Sirius Red, express strong ACE2 and TMPRSS2 staining. The rectangle frames are magnified on the right upper corners. 10X magnification. Scale bar: 100 μm. ACE2: angiotensin-converting enzyme 2; TMPRSS2: transmembrane serine protease 2; IPF: idiopathic pulmonary fibrosis

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