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Fig. 11 | Particle and Fibre Toxicology

Fig. 11

From: Respiratory and systemic impacts following MWCNT inhalation in B6C3F1/N mice

Fig. 11

T cell subtypes in the spleen following 30-day MWCNT exposure + 10 days recovery. a CD8+ cytotoxic T lymphocytes (CTL) as a percent of total T cells (CD3+ lymphocytes). Asterisks *** indicate significance at P < 0.001 compared to all other groups or * P < 0.05 compared to air control group. b Activated cytotoxic T lymphocytes expressing high levels of CD44 as a percent of total T cells. c CD4+ T helper cells as a percent of total T cells. Asterisk * indicate significance at P < 0.05 compared to all other groups. d Activated T helper cells expressing high CD44 as a percent of total T cells. Asterisks *** P < 0.001, ** P < 0.01 or *P < 0.05 compared to Air control group. e Ratio of CD4+ to CD8+ T cells. Asterisks *** indicate significance at P < 0.001 compared to all other groups or * P < 0.05 compared to air control group. All data expressed as mean ± SEM (n = 8)

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