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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Respiratory and systemic impacts following MWCNT inhalation in B6C3F1/N mice

Fig. 3

Cytokine changes in the lung lavage fluid of mice exposed to MWCNT following 30-day exposure + 10 days recovery. The first pull of cold saline lavage fluid was used to assess a panel of seven analytes. The MesoScale Discovery (MSD) system was used to assay for multiple analytes in a single sample. In the figure above, there was a significant observed increase in three of the seven inflammatory mediators including a IL-1β, b IL-6, and c TNF-α. Asterisks * indicate statistical significance at P < 0.05 compared to ‘Air’ control or *** where P < 0.001 compared to all other doses by Holm-Sydak post-hoc analyses. All data expressed as mean ± SEM (n = 8)

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