Skip to main content

Table 2 Body weight, body weight gain, and organ weight at the end of treatment (EoT) and recovery (Rec) period (n = 6). Data are expressed as mean value ± SD

From: Repeated oral administration of low doses of silver in mice: tissue distribution and effects on central nervous system

Time point Group Body weight at sacrifice (g) Body weight gain at sacrifice (%) Liver (g) Spleen (g) Kidneys (g)
EoT Control (vehicle) 35.58 ± 2.73 21.19 ± 6.19 2.50 ± 0.30 0.12 ± 0.05 0.66 ± 0.07
AgNP 0.25 mg/kg bwa 37.41 ± 2.28 30.76 ± 9.74 2.45 ± 0.30 0.12 ± 0.06 0.70 ± 0.07
AgNP 1 mg/kg bwa 35.93 ± 3.22 28.96 ± 6.,86 2.50 ± 0.29 0.10 ± 0.01 0.69 ± 0.07
AgAc 1.55 mg/kg bw 36.15 ± 1.60 21.24 ± 9.94 2.42 ± 0.31 0.12 ± 0.,03 0.66 ± 0.08
Rec Control (vehicle) 42.60 ± 3.33 47.2 ± 5.80 2.15 ± 0.30 0.10 ± 0.01 0.71 ± 0.05
AgNP 0.25 mg/kg bwa 42.62 ± 2.04 52.87 ± 9.89 2.24 ± 0.21 0.12 ± 0.02 0.71 ± 0.07
AgNP 1 mg/kg bwa 41.27 ± 2.08 47.30 ± 7.29 2.48 ± 0.20 0.11 ± 0.01 0.73 ± 0.05
AgAc 1.55 mg/kg bwb 40.12 ± 4.23 43.83 ± 14.12 2.25 ± 0.33 0.13 ± 0.05 0.69 ± 0.06
  1. aNominal dose (actual delivered doses were 0.20 and 0.80 mg/kg bw)
  2. bContaining the equivalent dose of 1 mg Ag/kg bw