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Table 1 Main characteristics of TiO2 P25, Printex-90, and MWNT-7 aerosols produced for inhalation studies

From: Retained particle surface area dose drives inflammation in rat lungs following acute, subacute, and subchronic inhalation of nanomaterials

Material Target concentration
(mg/m3)
Actual concentration
(mg/m3)
Number concentrationc
(particle×104/cm3)
MMADd
(μm)
CMoADe
(μm)
GSDe Aerosol effective density
(g/cm3)f
P25 15
15 (2-week)
5a
5a (2-week)
1.5a
1.5a (2-week)
15.3 ± 3.98
15.3 ± 3.54
5.02 ± 0.39
5.04 ± 1.30
1.59 ± 0.45
2.20 ± 0.64
5.1 ± 1.7 1.56 0.31 1.72 1.70
P25 5b 5.09 ± 0.65 27 ± 2 0.40 0.17 1.82 0.90
Printex-90 50
15a
5a
50.1 ± 3.89
15.0 ± 1.24
4.89 ± 0.39
35 ± 14 0.94 0.03
& 0.20
1.97
& 2.11
0.35
MWNT-7 1.5
0.5a
0.15a
1.69 ± 0.49
0.47 ± 0.15
0.13 ± 0.02
0.14 ± 0.05 1.78 0.40 1.69 0.45
  1. a6 h-equivalent concentration created by modulating the time for which animals were exposed to the aerosols produced from a dry powder generator
  2. baerosol produced from a nebulized suspension
  3. cMeasured by CPC particle diameter dp < 3 μm
  4. dDetermined from cascade impactor (DPLI+) sampling, subsequent gravimetric analysis and further data inversion to account for particle deposition probabilities [50]
  5. eDetermined from a log-normal fitting of the number size distribution provided either by SMPS or APS measurements
  6. fAerosol effective densities were estimated by merging SMPS and APS number size distributions and assuming spherical particles [51]. These data shall be considered as indicative values