Fig. 7

Schematic illustration of the molecular mechanism underlying of biomass combustion soluble constituent (BCSC)-induced cytotoxicity in human pulmonary alveolar epithelial cells (HPAEpiC). The p53 signaling pathway was activated after HPAEpiC exposure to BCSCs, significantly enhancing the expression of Bax, cleaved caspase-9, and cleaved caspase-3, and inhibiting Bcl-2 expression