Skip to main content
Fig. 1 | Particle and Fibre Toxicology

Fig. 1

From: Pulmonary delivery of the broad-spectrum matrix metalloproteinase inhibitor marimastat diminishes multiwalled carbon nanotube-induced circulating bioactivity without reducing pulmonary inflammation

Fig. 1

Experimental Design. Male C57BL/6 mice aged 6–8 weeks were randomized into 6 groups of 5 mice each. Animals were weighed and dosed with 10 mg/kg body weight Marimastat via oropharyngeal aspiration 1 h prior to dosing with dispersion media (DM; 0 µg), 10 µg, or 40 µg of MWCNT via oropharyngeal aspiration. Animals were euthanized 24-h post MWCNT exposure and tissues collected to assess pulmonary inflammation, serum peptide profile and serum bioactivity. (Figure generated in BioRender)

Back to article page

Particle and Fibre Toxicology

ISSN: 1743-8977

Contact us