Skip to main content
Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: The mechanism of cell death induced by silver nanoparticles is distinct from silver cations

Fig. 4

Both AgNPs and Ag+ increase ROS. A SUM159 and iMEC cells were treated with either Ag+ or AgNPs for 24 h with and without 100 IU peg-catalase. Cells were then incubated with PBS containing H2DCF-DA for 30 min and fluorescense was measured using confocal microscopy. Images were quantified in (B). Results shown in A as representative images from 3 independent experiments. Data in B is plotted as corrected total cell fluorescences ± SEM of at least 10 cells per image for 3 images. Statistical analysis was performed by one-way ANOVA followed by post-hoc Sidaks test. Significant differences are indicated (**p < 0.01; ***p < 0.001; ****p < 0.0001)

Back to article page