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Fig. 1 | Particle and Fibre Toxicology

Fig. 1

From: Serum peptidome: diagnostic window into pathogenic processes following occupational exposure to carbon nanomaterials

Fig. 1

The serum peptidome discriminated workers with acute CNT/F exposure. The serum peptidome was quantified across manufacturing workers grouped by Low (< 0.1 µg/m3 inhalable EC fraction) and High (> 0.5 µg/m3 inhalable EC fraction) CNT/F exposure across two workdays. a Relative peptide ion intensity is perspective-plotted by reduced mass and chromatographic retention time measures, illustrating significant differences between High and Low exposure groups. b Relative quantity across individual workers is shown by heatmap for the 934 statistically responsive serum peptides detected in ≥ 75% of workers. Data are plotted as log(2) fold change from the Low-group mean. c The serum peptidome response as illustrated by a volcano plot of fold-change from the Low-group mean plotted against p-values, with the significance threshold adjusted to a 5% FDR

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