Serum peptidome: diagnostic window into pathogenic processes following occupational exposure to carbon nanomaterials

Table 2 Cross-study comparison of cardiovascular-related blood biomarker responses to CNT/F exposure

Serum protein biomarker (or peptide parent)	Liou et al. (2012)	Liao et al. (2014)	Kuijpers et al. (2018)	Beard et al. (2018)	Mostovenko et al. (2019)	Current study
Serum protein biomarker (or peptide parent)	Cross-sectional	Longitudinal	Cross-sectional	Cross-sectional	Mouse Model	Case–control
ADAM15						Up
Fetuin-A					Up	Up
Albumin					Up & Down	Down
ARHGAP21						Down
COG8						Up
CPXM2						Up
F13A						Up
Fibrillin-1					Up	Up
Fibrinogen-A	Up	Unchanged	Unchanged	Up & Down	Down	Down
Fibrinopeptide-A					Up & Down	Up & Down
FLNC						Up
ICAM-1	Up	Unchanged	Up	Up
PLPP3						Down
t-PA			Unchanged	Down
VCAM-1	Unchanged	Up	Unchanged	Up
vWF (VWDE)			Unchanged	Down	Down	Down

ISSN: 1743-8977