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Table 5 Signaling pathways of differentially expressed upregulated genes at 1 month after exposure to 1.0 mg-CL-PAA (p < 0.05 and gene counts 2)

From: Inflammogenic effect of polyacrylic acid in rat lung following intratracheal instillation

Category

Term

Count1

%2

p-value3

Benjamini4

KEGG_PATHWAY

Cytokine-cytokine receptor interaction

31

5

7.00E−12

1.30E−09

KEGG_PATHWAY

Chemokine signaling pathway

29

4.7

1.10E−11

1.30E−09

  1. 1“Count” means the number of genes involved in the term
  2. 2“%” means percentage of “involved genes”/“total genes”
  3. 3,4Fisher’s exact test and modified Fisher’s exact test is adopted to measure the gene-enrichment in annotation terms, respectively
  4. The total number of genes analyzed was 618 genes in this analysis