Fig. 9
Exposure to inhaled DEP results in changes in microbial profiles which are mitigated in probiotic treated mice. Heat map shows the percent change in DEP or DEP + PRO compared to respective controls for most abundant phyla (A) and genus (B) in C57Bl/6 male mice on high-fat (HF) diet exposed to diesel exhaust particles (DEP- 35 μg PM) or saline control (CON) twice a week for four weeks with a subset of mice given 0.3 g/day (~ 7.5 × 107 cfu/day) of Ecologic® Barrier probiotics (PRO) in the drinking water throughout the exposures. An increase in bacteria with DEP exposure is indicated by a positive percentage (yellow) and a decrease in bacteria with DEP exposure is indicated by a negative percentage (black). Values can be viewed in Table 3