Inhaled diesel exhaust particles result in microbiome-related systemic inflammation and altered cardiovascular disease biomarkers in C57Bl/6 male mice

Table 4 AMOVA analysis of microbial profiles from small intestine

Exposure Groups	SS	Df	MS	Fs	p-value
HF + CON- versus HF + CON + PRO versus HF + DEP versus HF + DEP + PRO				3.57114	0.002
Among	2.08605	3	0.69535
Within	4.86785	25	0.19471
Total	6.9539	28
HF + CON versus HF + CON + PRO				7.80237	0.001
Among	1.37017	1	1.37017
Within	2.28292	13	0.17561
Total	3.65309	14
HF + CON versus HF + DEP				1.14753	0.364
Among	0.26276	1	0.262757
Within	2.97668	13	0.228976
Total	3.23944	14
HF + CON versus HF + DEP + PRO				4.92282	0.003
Among	0.98308	1	0.983079
Within	2.59608	13	0.199698
Total	3.57916	14
HF + CON + PRO versus HF + DEP				4.02749	0.006
Among	0.76246	1	0.762461
Within	2.27177	12	0.189314
Total	3.03423	13
HF + CON + PRO versus HF + DEP + PRO				1.30782	0.265
Among	0.20611	1	0.206109
Within	1.89117	12	0.157597
Total	2.09728	13
HF + DEP versus HF + DEP + PRO				2.55175	0.032
Among	0.549675	1	0.549675
Within	2.58493	12	0.215411
Total	3.13461	13

DEP, diesel exhaust particles; CON, saline controls; HF, high-fat diet; LF, low-fat diet; SS, sum of squares; Df; degrees of freedom; MS, mean of squares

ISSN: 1743-8977