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Fig. 8 | Particle and Fibre Toxicology

Fig. 8

From: Nano-titanium dioxide inhalation exposure during gestation drives redox dysregulation and vascular dysfunction across generations

Fig. 8

taken from RASMC cell culture showing rapid phosphorylation of MLC. B H2O2 production capacity rate in isolated uterine arteries. Elevated H2O2 capacity in F1 TiO2 uterine vasculature at GD 20. C An ELISA for estradiol was on plasma from F1 females born to sham-control (n = 9) or nano-TiO2 dams (n = 12). *p < 0.05 Sham-control group versus nano-TiO2-exposed groups

Endocrine and reactive oxygen species disruption in F1 dams at gestational day 20. A Kiss treatment of rat aortic smooth muscle cells (RASMC) resulted in a rapid phosphorylation of myosin light chain (MLC) in vascular smooth muscle cells. Representative imagine

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