Fig. 1

Body weight gain (%) of C57BL/6J (A, C) and 5xFAD (B, D) mice during 3 weeks (A, B) or 14 weeks (C, D) exposure to CeO₂ or SiO₂ [0.1% or 1%] in feed pellets ad libitum. Statistical analysis was performed using ANOVA followed by Dunnett evaluation; *p < 0.05 and **p ≤ 0.01 versus mice exposed to control feed pellets. Number of animals per group: 3 weeks C67BL/6J control (n = 6); SiO₂ 0.1% (n = 6); SiO₂ 1% (n = 7); CeO₂ 0.1% (n = 6). CeO₂ 1% (n = 6); 5xFAD control (n = 10); SiO₂ 0.1% (n = 10); SiO₂ 1% (n = 9); CeO₂ 0.1% (n = 10). CeO₂ 1% (n = 10); 14 weeks C67BL/6J control (n = 5); SiO₂ 0.1% (n = 6); SiO₂ 1% (n = 6); CeO₂ 0.1% (n = 6). CeO₂ 1% (n = 6); 5xFAD control (n = 11); SiO₂ 0.1% (n = 9); SiO₂ 1% (n = 10); CeO₂ 0.1% (n = 10). CeO₂ 1% (n = 10)