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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Ultrasmall iron oxide nanoparticles cause significant toxicity by specifically inducing acute oxidative stress to multiple organs

Fig. 3

Detection of the generated ROS. Fluorescence images showing the ROS of MCF-7 cells after incubation with different-sized Fe3O4 (a), SiO2 (c), and Au (e) with a concentration of 500 μg/mL for 2 h and 6 h. Green fluorescence: DCFH-DA, an indicator of ROS; blue fluorescence: Hoechst 33,342. The corresponding fluorescence intensities of DCFH in MCF-7 cells after incubation with different-sized Fe3O4 (b), SiO2 (d), and Au (f) for 2 h and 6 h. All of the data were presented as the mean ± SD (n = 3). P values: ***P < 0.001

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