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Fig. 11 | Particle and Fibre Toxicology

Fig. 11

From: Dose–response relationship of pulmonary disorders by inhalation exposure to cross-linked water-soluble acrylic acid polymers in F344 rats

Fig. 11

Dose-dependent induction of biochemical markers in the BALF obtained from the lungs of rats after inhalation of CWAAP-A for 13 weeks. Lactate dehydrogenase (LDH) activity (a, b), phospholipid (PL) concentration (c, d), alkaline phosphatase (ALP) activity (e, f), γ-glutamyl transpeptidase (γ-GTP) activity (g, h) were measured using an automatic analyzer, and are shown by sex (males: a, c, e and g; females: b, d, f and h). Statistical significance was analyzed using William’s multiple comparison test compared with age-matched control (0 mg/m3) groups: *p < 0.025, **p < 0.005 and ***p < 0.0005

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