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Fig. 13 | Particle and Fibre Toxicology

Fig. 13

From: Dose–response relationship of pulmonary disorders by inhalation exposure to cross-linked water-soluble acrylic acid polymers in F344 rats

Fig. 13

Induction of transforming growth factor (TGF) β and hydroxyproline, a major component of collagen fibers, in the lungs of rats exposed to CWAAP-A by inhalation for 13 weeks. The concentrations of TGFβ1 and TGFβ2 in the BALF were measured by enzyme immunoassay, and represented in panels a and c for males and in panels b and d for females. Hydroxyproline content in the lungs of males (e) and females (f) was determined using a commercially available colorimetric kit. William’s multiple comparison test compared with age-matched control (0 mg/m3) groups: *p < 0.025, **p < 0.005 and ***p < 0.0005

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Particle and Fibre Toxicology

ISSN: 1743-8977

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