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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Assessment of the toxicity and carcinogenicity of double-walled carbon nanotubes in the rat lung after intratracheal instillation: a two-year study

Fig. 3

Lung sections of rats administered 0.5 mg DWCNT at 52 weeks (A) and 104 weeks (B). The majority of the DWCNT is encapsulated in granulation tissue (arrows). The boxed areas are higher magnifications using a polarized lens showing DWCNT fibers. Lung sections of rats administered MWCNT (0.5 mg) at 52 weeks (C) and 91 weeks (D). MWCNT-7 can be seen encapsulated inside granulation tissue. In contrast to DWCNT, free macrophages phagocytosing MWCNT-7 fibers are a common feature. The boxed areas are higher magnifications using a polarized lens showing MWCNT fibers in free macrophages

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