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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Chronic effects of two rutile TiO2 nanomaterials in human intestinal and hepatic cell lines

Fig. 2

TEM images of differentiated HepaRG cross sections showing the uptake of NM-103 (A, C, E, G, I) and NM-104 (B, D, F, G, J) exposed to 50 (A–D) or 12.5 µg/cm2 (E–H). Differentiated HepaRG cells were treated for 24 h (A, B), 24 h with a 1-week recovery period (C, D), 1 week (E, F), 1 week with a 1-week recovery period (G, H), or 2 weeks (I, J). NM aggregates in cell cytoplasm increase over time

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