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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Chronic effects of two rutile TiO2 nanomaterials in human intestinal and hepatic cell lines

Fig. 4

Ion reconstructions of a 3D depth profile of HepaRG cells exposed to TiO2 nanoparticles at a concentration of 3.13 µg/cm2 (NM-103: A–C, NM-104: D–F) for 1 week (A, D), 2 weeks (B, E) and for 1 week with a 1-week recovery period (C, F). Cell outlines are shown in solid blue and were reconstructed from the C3H8N + signal from phosphatidylcholine, and intracellular TiO2 NMs are shown in red

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