Skip to main content
Fig. 5 | Particle and Fibre Toxicology

Fig. 5

From: Oxidative stress generated by polycyclic aromatic hydrocarbons from ambient particulate matter enhance vascular smooth muscle cell migration through MMP upregulation and actin reorganization

Fig. 5

Effect of PAHs and oxy-PAHs on the expression of ROS-dependent signals. a The mRNA levels of CYP1A1 in the absence or presence of NAC were evaluated by qPCR. b The effect of NAC treatment on the nuclear translocation of Nrf2 was evaluated by immunocytochemistry. c The mRNA levels of Nrf2, HO-1, and NQO1 in the absence or presence of NAC were evaluated by qPCR. d The expression levels of NQO1 and phosphorylated Src were analyzed by western blotting. Protein levels were normalized to β-actin. All values are represented as mean ± SD. ***P < 0.001 versus control; $P < 0.05, $$P < 0.01, and $$$P < 0.001 PAHs with NAC versus PAHs alone

Back to article page

Particle and Fibre Toxicology

ISSN: 1743-8977

Contact us