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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: TFEB-lysosome pathway activation is associated with different cell death responses to carbon quantum dots in Kupffer cells and hepatocytes

Fig. 4

CD-induced autophagy mediated different apoptosis outcomes in the two cell types. A–J After 12 h treatment with 0 and 400 μg/mL CDs, expression of autophagy-related proteins, LC3 and Cleaved caspase3, were detected in KUP5 and AML12 cells. In the autophagy inhibitor group, KUP5 and AML12 cells were pretreated with 1 mM 3-MA for 2 h before treatment. N = 3 replications. All values are mean ± SD. The statistical significance of differences was evaluated by one-way ANOVA. Compared with the control group. *, P < 0.05. #Compared with the untreated 3-MA group, P < 0.05

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Particle and Fibre Toxicology

ISSN: 1743-8977

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