Fig. 9
From: Impact of in vitro digested zinc oxide nanoparticles on intestinal model systems
Relative metabolic activity of Caco-2 monocultured (a) and Caco-2/HT29-MTX cocultured cells (b) after 24 h of treatment with digested ZnO NP (< 50 nm and < 100 nm) and ZnCl2. SC: solvent control (10% intestinal juice); PC: positive control (0.1% triton X-100 + 10 mM EGTA apical, 10 mM EGTA basolateral). Data are normalized to the untreated control (= 100%; dashed line) and expressed as mean + SD; n = 3. Significant differences compared to the untreated control (***P ≤ 0.001) were obtained by using the unpaired t test