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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Murine in utero exposure to simulated complex urban air pollution disturbs offspring gut maturation and microbiota during intestinal suckling-to-weaning transition in a sex-dependent manner

Fig. 3

Epithelium proliferation, differentiation, and maturation in male mice. A Representative pictures of PCNA-stained proximal colon from control air- and Beijing-like air-exposed mice, scale bar 50 µm (n = 10/group). B Number of PCNA positive cells/crypt. C Lgr5 transcript levels. D Alpi, Epcam, and Car2 transcript levels. E Muc2, Lyz1, ChrgA, and Pou2f3 transcript levels. F Ass1, Fcgrt, Prdm1, and Lct transcript levels. G Treh, Arg2, and Sis transcript levels. H Representative pictures of PCNA-stained ileum from control air- and Beijing-like air-exposed mice, scale bar 50 µm (n = 10/group). I Number of PCNA-positive cells/crypt. J Lgr5 transcript levels. K Alpi, Epcam, and Car2 transcript levels. L Muc2, Lyz1, ChrgA, and Pou2f3 transcript levels. M Ass1, Fcgrt, Prdm1, and Lct transcript levels. N Treh, Arg2, and Sis transcript levels. *p < 0.05, **p < 0.01, ***p < 0.005 as determined by the Mann–Whitney U test

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Particle and Fibre Toxicology

ISSN: 1743-8977

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