Particle and Fibre Toxicology

Table 3 The relationships between LogOPN and 1-OHP in non-smoking subjects used for linear regression models

From: Aryl hydrocarbon receptor activation-mediated vascular toxicity of ambient fine particulate matter: contribution of polycyclic aromatic hydrocarbons and osteopontin as a biomarker

	Univariate analysis				Model 1 (stepwise)^a				Model 2 (stepwise)^b				Model 3 (stepwise)^c
	B	95%CI		p-value	B	95%CI		p-value	B	95%CI		p-value	B	95%CI		p-value
Log1-OHP	1.11	0.64	1.57	< 0.001	0.88	0.42	1.35	< 0.001
1-OHP (≥ 0.083 ng/ml vs. < 0.083 ng/ml)	0.69	0.27	1.10	0.002					0.43	0.02	0.84	0.041
1-OHP(µg/g creatinine)	2.18	0.05	3.86	0.012									1.86	0.30	3.42	0.020
Age (year)	− 0.09	− 0.16	− 0.02	0.009
BMI (Kg/m²)	0.04	− 0.02	0.11	0.163
Waist circumstances (cm)	0.01	− 0.01	0.04	0.297
Time spent indoors (hours)	− 0.06	− 0.12	0.004	0.065					− 0.05	− 0.10	0.01	0.07
Time spent outdoors (hours)	0.07	− 0.02	0.15	0.118
Transit time (hours)	0.12	− 0.24	0.47	0.504
Gender (Male vs. Female)	0.44	− 0.01	0.88	0.053	0.34	− 0.02	0.71	0.063	0.40	0.02	0.78	0.041
Alcohol drinking (Yes vs. No)	0.03	− 0.32	0.38	0.859
Vitamin supplement (Yes vs. No)	− 0.92	− 1.40	− 0.43	< 0.001	− 0.53	− 1.00	− 0.07	0.025	− 0.65	− 1.13	− 0.16	0.010	− 0.62	− 1.00	− 0.24	0.002
Medicine taken (Yes vs. No)	− 0.84	− 1.83	0.16	0.098
Regular exercise (Yes vs. No)	− 0.09	− 0.38	0.21	0.545

^aThe predictive variables including Log1-OHP, age, BMI, waist circumstances, time spent indoors, gender, alcohol drinking, vitamin supplement, and regular exercise
^bThe predictive variables including 1-OHP (median categories), age, BMI, waist circumstances, time spent indoors, gender, alcohol drinking, vitamin supplement, and regular exercise
^cThe predictive variables including 1-OHP(µg/g creatinine), age, BMI, waist circumstances, time spent indoors, gender, alcohol drinking, vitamin supplement, and regular exercise

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ISSN: 1743-8977

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