Fig. 5

Absolute quantitative lipidomics verified changes of the concentrations of PCs in serum. Compared with the control group, the concentration of three kinds of PCs in serum of the 50 mg/kg TiO2 NPs treated group changed significantly. PC(16:0/20:1) increased significantly, while PC(18:0/18:0) and PC(18:2/20:2) decreased significantly. Significant difference compared with the control group (∗ p < 0.05)