Fig. 6

Mineral particle-induced lysis of human erythrocytes. Human erythrocytes harvested from donors were exposed to 0–400 µg/mL Na-feldspar, K-feldspar, Ca-feldspar, biotite, epidote, hornblende, actinolite, augite, quartz and orthopyroxene for 30 min. Free hemoglobin in the supernatant, an indicator of cell lysis, was detected by reading absorbance at 540 nm. Results are presented as mean ± SD (n = 3). Area under the curve (AUC) values in B were calculated from the values in A for the concentration-range of 0–400 µg/mL. Statistical significance is based on a two-way ANOVA followed by Dunnet’s post-test (A) or a one-way ANOVA followed by Tukey post-test (B). All values were log-transformed prior to statistical analysis to satisfy model assumptions. Asterisks (*) indicate statistically significant difference from the respective control (A), while a capped line indicates statistically significant difference between particle samples (B)