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Table 3 Apparent permeability (Papp) values of Caco-2 barrier model after 24 h of incubation

From: Changes of physico-chemical properties of nano-biomaterials by digestion fluids affect the physiological properties of epithelial intestinal cells and barrier models

 

Untreated Papp (cm/s)

SHDS-treated Papp (cm/s)

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2.61 × 10–7 ± 2.71 × 10–8

2.67 × 10–7 ± 1.40 × 10–8

LSNPs

2.32 × 10–7 ± 5.60 × 10–9

2.26 × 10–7 ± 3.20 × 10–9

CNPs

2.38 × 10–7 ± 1.83 × 10–8

2.09 × 10–7 ± 3.37 × 10–9

FNPs

2.29 × 10–7 ± 1.08 × 10–8

2.50 × 10–7 ± 1.35 × 10–8

HNPs

2.21 × 10–7 ± 9.92 × 10–9

2.18 × 10–7 ± 1.45 × 10–8

  1. 24 h of incubation with 50 µg/ml of LSNPs and FNPs, and 150 µg/ml of CNPs and HNPs. n = 3; mean ± SEM
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Particle and Fibre Toxicology

ISSN: 1743-8977

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