Fig. 10From: Pulmonary dust foci as rat pneumoconiosis lesion induced by titanium dioxide nanoparticles in 13-week inhalation studyCell proliferative activity of AEC2. Representative immunohistochemical staining images of Ki67, a cell proliferation marker, and LPCAT1, an AEC2 marker (A). The Ki67-positive index in AEC2 was calculated as the percentage of Ki67 and LPCAT1 double positive cells compared to the total LPCAT1-positive cell population (B) (n = 5). Statistical significance was analyzed using two-way ANOVA with Tukey’s multiple comparison test: ***p < 0.001 indicate significant differences. Abbreviations: PDF: pulmonary dust foci and SUR: tissue surrounding a lesionBack to article page