Fig. 6From: A systematic quality evaluation and review of nanomaterial genotoxicity studies: a regulatory perspectiveThe breakdown of the in vivo genotoxicity assay-specific evaluation results by obligatory criteria. The percentage and number of assays (out of the total number of assays evaluated for each criterion) that fulfilled each assay-specific criterion is presented in each bar. *This criterion was not required for the gene mutation assay. A test that followed an older (1997) version of the corresponding OECD guideline, and had clearly positive results, was considered acceptable for micronucleus and chromosomal aberration assay. **Tests with positive results were accepted whatever treatment or sampling schedule usedBack to article page