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Fig. 4 | Particle and Fibre Toxicology

Fig. 4

From: Amine-modified nanoplastics promote the procoagulant activation of isolated human red blood cells and thrombus formation in rats

Fig. 4

Measurement of the mechanism underlying coagulation activation in human RBCs. After RBCs were treated with various concentrations of PS-NPs for 3 h, intracellular calcium levels (n = 5) (A) were detected. Depletion of intracellular ATP levels (n = 4) (B) and GSH levels (n = 6) (C) were observed after RBCs were exposed to PS-NPs. Scramblase activity was determined by measuring the translocation 10 min after C6-NBD-PC treatment (n = 7) (D). Data are presented as the mean ± SE. *p < 0.05, **p < 0.01, ***p < 0.001 versus control (CON)

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Particle and Fibre Toxicology

ISSN: 1743-8977

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