Fig. 5

Effects of PS-NPs on the adhesion of human RBCs to human umbilical vein endothelial cells (HUVECs) and thrombin generation. A Adhesion of RBCs incubated with PS-NPs to HUVECs was observed using fluorescence microscopy (n = 4). The signal of endothelial cells is green fluorescence and that of RBCs is red fluorescence. The white circles indicate the aggregated RBCs. B Thrombin generation was determined at the various concentrations of PS-NPs at a wavelength of 405 nm (n = 6). Data are presented as the mean ± SE. *p < 0.05, **p < 0.01, ***p < 0.001 versus control (CON)