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Fig. 3 | Particle and Fibre Toxicology

Fig. 3

From: Dimethylarginine dimethylaminohydrolase 1 protects PM2.5 exposure-induced lung injury in mice by repressing inflammation and oxidative stress

Fig. 3

Ddah1 deficiency aggravates lung inflammation in PM2.5-exposed mice. A Representative lung sections were stained with antibodies specific for neutrophils (Scale bar = 100 μm), F4/80, ICAM-1 and VCAM-1 (Scale bar = 50 μm). The relative neutrophil B or F4/80 C positive cell numbers and the levels of ICAM-1 (D) and VCAM-1 E were quantified. F The ADMA levels in lung tissue were measure. G–I The mRNA expression levels of TNFα, IL-6 and IL-1β in the lung tissues were measured. In Figure B–E, N = 6; In Figure F–I, N = 5; data are presented as the mean ± SD; *indicates p < 0.05, **indicates p < 0.01

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