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Table 4 Repeated measures correlations between change in symptoms and airway function measures

From: Concentration-dependent increase in symptoms due to diesel exhaust in a controlled human exposure study

Symptom category (at 4 h)

Correlate

Timepoint (h)

r (std error)

P value

Total

Percentage ΔFeNO

4

0.29 (0.13)

0.04

  

24

0.39 (0.12)

 < 0.00

 

Percentage ΔFEV1

4

0.04 (0.14)

0.78

  

24

0.07 (0.14)

0.64

 

Δlog PC20

24

− 0.06 (0.15)

0.71

Constitutional

Percentage ΔFeNO

4

0.12 (0.14)

0.41

  

24

0.34 (0.13)

0.02

 

Percentage ΔFEV1

4

0.04 (0.14)

0.79

  

24

0.17 (0.14)

0.24

 

Δlog PC20

24

− 0.02 (0.15)

0.91

Eyes

Percentage ΔFeNO

4

0.32 (0.13)

0.02

  

24

0.40 (0.12)

 < 0.00

 

Percentage ΔFEV1

4

0.04 (0.14)

0.78

  

24

0.09 (0.14)

0.55

 

Δlog PC20

24

− 0.07 (0.15)

0.65

  1. Symptom scores were summed into categories
  2. Significant effects (P < 0.05) are bolded