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Fig. 2 | Particle and Fibre Toxicology

Fig. 2

From: Grouping of orally ingested silica nanomaterials via use of an integrated approach to testing and assessment to streamline risk assessment

Fig. 2

A Dissolution half-time (t1/2) of the selected NFs (1 mg/mL) measured after 155 min of OGI digestion (= after 30 min of intestinal phase). Data are expressed in hours and as mean ± standard deviation (n = 3) * p ≤ 0.05 vs Silica-Silane. B Similarity assessment by Bayes Factor (BF) pairwise analysis for selected NFs (value are scaled between 0 and 1) based on % of NF dissolution (ratio between % ‘dissolved’ of one NF by the other) together with the half-time values in OGI fluids. Values close to zero (blue color) indicate that the NFs are not similar and values close to one (red color) indicate similarity between NFs

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