Acute phase response following pulmonary exposure to soluble and insoluble metal oxide nanomaterials in mice

Table 3 Pearson correlation coefficient (r) obtained between outcomes and NM dose expressed as surface area or mass

Day	Outcomes	Log dosed surface area		Log dosed mass
Day	Outcomes	Soluble NMs	Insoluble NMs	Soluble NMs	Insoluble NMs
Day 1	Log Neutrophils	0.61*	0.75***	0.47	0.73***
	Log Saa3 mRNA level	0.25	0.70***	0.38	0.82***
	Log SAA3	0.50	0.92*	0.67	0.98***
	Log Saa1 mRNA level	0.17	-0.04	0.23	0.27
	Log SAA1	0.34	0.83*	0.25	0.67
Day 28	Log Neutrophils	-0.64*	0.73***	-0.62*	0.56***
	Log Saa3 mRNA level	-0.64*	0.32	-0.53	0.51**
	Log Saa1 mRNA level	-0.68	0.66	-0.74	0.58

ISSN: 1743-8977